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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Pain. 2022 Mar 1;163(3):436–444. doi: 10.1097/j.pain.0000000000002372

Table 2:

Adjusted analyses assessing effects of group and time on sleep and psychosocial factors in episodic migraine patients

Variable Mean Difference (95% Confidence Interval) p valuea
Sleep Quality (PSQI) b
Group effect
MBSR+ vs. SMH −0.42 (−1.39, 0.55) 0.39
Time effect
Δ 10 weeks −0.13 (−0.70, 0.45) 0.66
Δ 20 weeks −0.67 (−1.10, −0.24) 0.0025
Anxiety (GAD-7) c
Group Effect
MBSR+ vs. SMH −0.13 (−0.71, 0.46) 0.67
Time Effect
Δ 10 weeks −0.20 (−0.66, 0.25) 0.38
Δ 20 weeks 0.14 (−0.26, 0.55) 0.48
Depression (PHQ-9) d
Random effects variance parameter
Intercept 2.62 (1.85, 3.98)
Residual 2.23 (1.83, 2.78)
Group Effect
MBSR+ vs. SMH −0.14 (−0.88, 0.61) 0.72
Time Effect
Δ 10 weeks 0.35 (−0.09, 0.80) 0.12
Δ 20 weeks −0.11 (−0.57, 0.35) 0.64
Stress (PSS) e
Group Effect
MBSR+ vs. SMH −0.93 (−2.49, 0.62) 0.24
Time Effect
Δ 10 weeks 0.09 (−0.84, 1.03) 0.85
Δ 20 weeks −0.49 (−1.65, 0.67) 0.40

Abbreviations: PSS: perceived stress score, GAD-7: generalized anxiety disorder, PHQ-9: patient healthy questionnaire, PSQI: Pittsburgh sleep quality index

a

p value from linear mixed model

b

Model adjusted for stress, BMI and headache pain

c

Model adjusted for stress and depression.

d

Model adjusted for anxiety, headache impact score and additional idiopathic pain condition. Model includes random intercept.

e

Model adjusted for depression, anxiety, sleep and headache days