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. 2021 Nov 3;34(6):1414–1423. doi: 10.1007/s10278-021-00530-6

Table 2.

True negative rate (TNR) achieved by our model when its false-negative rate (FNR) are 0.01, 0.02, 0.03 and 0.05 as we vary prediction threshold for assigning observations to a positive class indicating malignancy. The 95% confidence interval of the estimated TNR and the clinical meaning are also provided

clinical meaning FNR TNR 95% CI of TNR
1.7% unnecessary biopsies we can help to avoid while missing no malignancies 0.00 0.017 [-0.005,0.040]
13.5% unnecessary biopsies we can help to avoid while missing 1% malignancies 0.01 0.135 [0.039, 0.232]
23.1% unnecessary biopsies we can help to avoid while missing 2% malignancies 0.02 0.231 [0.190, 0.273]
27.6% unnecessary biopsies we can help to avoid while missing 3% malignancies 0.03 0.276 [0.240, 0.312]
43.5% unnecessary biopsies we can help to avoid while missing 5% malignancies 0.05 0.435 [0.407, 0.562]