Table 2.
SNPs displaying significant association with the susceptibility to agitation by GWAS (n = 30).
| CHR | SNP | Gene | Allele | Position | P -value | R 2 |
|---|---|---|---|---|---|---|
| 4 | rs11932717 | / | A > C | 175,950,601 | 6.50 × 10−7 | 0.68 |
| X | rs1588064 | / | G > A | 115,892,959 | 7.68 × 10−7 | 0.33 |
| 5 | rs3733784 | MTRR | T > C | 7,862,926 | 1.92 × 10−6 | 0.58 |
| 5 | rs2307116 | MTRR | G > A | 7,861,985 | 3.02 × 10−6 | 0.70 |
| 5 | rs1801394 | MTRR | A > G | 7,870,973 | 3.02 × 10−6 | 0.70 |
GWAS, genome-wide association study; SNPs, single-nucleotide polymorphisms; CHR, chromosome; R2, Linkage Disequilibrium Analysis; MTRR, methionine synthase reductase.