Figure 2.
BART10-3p is increased in NPC tissues and correlates with unfavorable prognosis. (a) Heatmap of differentially expressed EBV-encoded miRNAs identified from the microarray dataset GSE32960 which contains 18 non-cancer tissues and 312 NPC tissues. Threshold was set at absolute fold change > 2 and adjusted P < 0.05. Columns: individual samples; rows: EBV-encoded miRNAs; blue: low expression; yellow: high expression. (b) Volcano plot for visualization of evidently differentially expressed miRNAs in the microarray dataset GSE32960. (c) Relative BART10-3p expression determined in the microarray dataset GSE36682 comprising 6 non-cancer tissues and 62 NPC tissues. (d) Relative BART10-3p expression determined in the microarray dataset GSE70970 which included 17 normal nasopharyngeal epithelial tissues and 246 NPC tissues. (e) Kaplan–Meier analysis of overall survival (OS), disease-free survival (DFS), and distant metastasis-free survival (DMFS) in patients stratified by BART10-3p expression. The log-rank test was used to calculate the P values. **P < 0.01.
