Figure 7.
BART10-3p facilitates NPC xenograft tumor growth in vivo. SUNE-1 cells were subcutaneously injected into the right axillary region of nude mice. After the tumor volume reached 50–100 mm3, intratumoral injection of 5 nM agomir-BART10-3p or agomir-NC (n = 5 per group) was performed. (a) Photograph of xenograft mice. (b) Photograph and weights of xenograft tumors. (c) Tumor growth curves of xenograft mice. The arrows indicate intratumoral injection of 5 nM agomir-BART10-3p or agomir-NC every three days. (d) Immunohistochemical staining for ALK7 expression in xenograft tumors. Scale bar, 100 μm. Data are presented as mean (n = 5) ± SEM. *P < 0.05, **P < 0.01.