Table 2.
Characteristics of sCAA patients with intragyral hemorrhage compared to sCAA patients without intragyral hemorrhage.
| sCAA with intragyral hemorrhage (n = 4) | sCAA without intragyral hemorrhage (n = 29) | |
|---|---|---|
| Median age in years (range) | 64.5 (62–71) | 71 (55–83) |
| Symptomatic ICH (%) | 4 (100) | 15 (52) |
| Median number of symptomatic lobar ICH (range) | 1.5 (1–2) | 0.5 (0–2) |
| ICH on MRI (%) | 4 (100) | 17 (59) |
| Lobar ICH (%) | 4 (100) | 17 (59) |
| Deep ICH (%) | 1 (25) | 2 (7) |
| Median lobar ICH count (range) | 6.5 (4–10) | 1.0 (0–9) |
| Median deep ICH count (range) | 0.0 (0–2) | 0.0 (0–1) |
| Median lobar microbleed count (range) | >50 (42 – >50) | 15 (0 – >50) |
| Median deep microbleed count (range) | 9.5 (0–36) | 0 (0–11) |
| Median Fazekas score periventricular (range) a | 3 (2–3) | 3 (1–3) |
| Median Fazekas score deep (range) a | 3 (2–3) | 2 (1–3) |
| Enlarged CSO-EPVS (%) b | 3 (100) | 12 (100) |
| 11–20 CSO-EPVS (%) | 0 (0) | 2 (17) |
| 21–40 CSO-EPVS (%) | 0 (0) | 2 (17) |
| >40 CSO-EPVS (%) | 3 (100) | 8 (67) |
| Median MMSE score (range) c | 20 (17–24) | 28 (18–30) |
| Median MOCA score (range) d | 18 (13–21) | 24 (13–29) |
| cSS (%) | 2 (50) | 19 (66) |
| Focal (%) | 1 (25) | 2 (7) |
| Disseminated (%) | 1 (25) | 17 (59) |
| Median hemisphere score (range) | 0.5 (0–4) | 2.0 (0–4) |
Note: MRI: magnetic resonance imaging; ICH: intracerebral hemorrhage; sCAA: sporadic cerebral amyloid angiopathy; CSO-EPVS: enlarged perivascular spaces in the centrum semiovale; MMSE: Mini Mental State Exam; MOCA: Montreal Cognitive Assessment; cSS: cortical superficial siderosis.
Intragyral hemorrhage participants n = 3, CAA participants without intragyral hemorrhage n = 28, due to missing MRI sequences.
Intragyral hemorrhage participants n = 3, CAA participants without intragyral hemorrhage n = 12, due to missing MRI sequences.
Intragyral hemorrhage participants n = 3, CAA participants without intragyral hemorrhage n = 27.
Intragyral hemorrhage participants n = 3, CAA participants without intragyral hemorrhage n = 28.