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. 2021 Jul 8;41(12):3288–3301. doi: 10.1177/0271678X211029060

Figure 2.

Figure 2.

Expression levels of proteins in the Nrf2-BDNF-TrkB pathway decrease after c-ICH in WT mice. Representative immunoblot from WT mice (a) and quantification of optical density (b) showed a marked decrease in expression of Nrf2, HO-1, BDNF, and TrkB on day 28 after c-ICH. (c) Representative images and quantification of BDNF immunofluorescent intensity on day 28 after sham surgery or c-ICH. Scale bar = 50 μm. (d) Representative images and quantification of cells positive for TrkB immunoreactivity on day 28 after sham surgery or c-ICH. Scale bar = 50 μm. Values are mean ± SD; n = 6 male mice per group. *p < 0.05 vs. sham group.