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Top to bottom: Dual-echo (no preload) and single-echo (with preload) signals (normalized to baseline), ΔR2* curves in a brain tumor ROI, corresponding AIF, and tumor T1-weighted curves (dual-echo only) for each protocol (left to right). All curves are from GBM patients. T1 leakage effects can be observed in the signals for the dual-echo acquisition (particularly TE1), which are removed in the dual-echo ΔR2*.
