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. 2019 Jul 19;14 Pt B:66–73. doi: 10.1016/j.clinms.2019.07.003

Table 2.

Comparison of recTDP-43 dilution series against detection criteria of S/N ≥ 3 and PAR within ±15% of expected (ePAR) for TDP252-263.

TDP-43 (ng/mL) S/N % from ePARa
Qualifier-1 (448.5 m/z) Qualifier-2 (758.6 m/z)
500 >100 −4 0
250 >100 −4 0
125 >100 −11 0
62.5 >100 −14 0
31.25 >100 −4 −11
15.63 >100 −11 −11
7.81 >73 −11 −11
3.91 >35 −11 −11
1.95b >22 −14 −56
0.98b >16 −4 −22
0.49b 8 +36 −22
0.24b 3 −25 +11
a

Deviation from the expected peak area ratio for recTDP-43.

b

Failed detection criteria.