TABLE 2.

Characteristics of clusters partitioned by k-medoids clustering^a

Cluster	No. of genes	Characteristic	Enriched functional groups
1	116	Up in C. parapsilosis	NA
2	174	Up generally, but more in C. albicans/C. dubliniensis	Organic acid metabolism, lipid metabolism, amino acid metabolism
3	202	Up in C. albicans, C. tropicalis, C. parapsilosis, L. elongisporus	Organic acid metabolism, amino acid metabolism, peroxisome organization
4	73	Up in C. lusitaniae	Hexose metabolism and transport
5	128	Up in C. tropicalis, down in C. parapsilosis	Sulfate assimilation, cytoplasmic translation
6	89	Down in C. tropicalis and C. lusitaniae	Septation initiation signaling
7	218	Down in C. albicans, C. tropicalis, C. parapsilosis, L. elongisporus	Ribosome biogenesis, ncRNA processing, aspartate metabolism

^aFor each cluster as visualized in Fig. 3, the number of genes, characteristic pattern, and functional groupings based on GO term analysis are shown. Full cluster information is found in Table S2. NA, not available; ncRNA, noncoding RNA.