Table 3.
Underlying cause of death for 283 decedents for 2002–2015 incident diabetes cases through 31 December 2017 by diabetes type: the SEARCH for Diabetes in Youth Study
| Diabetes type | |||||
|---|---|---|---|---|---|
| ICD-10 codes | Type 1, N (%) | Type 2, N (%) | Secondary, N (%) | Other/unknown,* N (%) | |
| Deaths from all causes, N | — | 133 | 55 | 87 | 8 |
| Underlying cause of death | |||||
| Certain infectious and parasitic disease | A00–B99 | 1 (0.8) | 2 (3.6) | 5 (5.7) | 0 |
| Cancer/neoplasms | C00–D48 | 1 (0.8) | 6 (10.9) | 10 (11.5) | 2 (25.0) |
| Diseases of the blood and blood-forming organs | D50–D89 | 1 (0.8) | 2 (3.6) | 2 (2.3) | 0 |
| Diabetes | E00–E14 | 56 (42.1) | 5 (9.1) | 4 (4.6) | 1 (12.5) |
| Type 1 diabetes with ketoacidosis | E10.1 | 12 (9.0) | 0 | 0 | 0 |
| Type 1 diabetes with renal complications | E10.2 | 0 | 0 | 0 | 1 (12.5) |
| Type 1 diabetes with without complications | E10.9 | 6 (4.5) | 0 | 0 | 0 |
| Unspecified diabetes, with coma | E14.0 | 1 (0.8) | 1(1.8) | 0 | 0 |
| Unspecified diabetes, with ketoacidosis | E14.1 | 25 (18.8) | 2 (3.6) | 0 | 0 |
| Unspecified diabetes with renal complications | E14.2 | 0 | 1 (1.8) | 1 (1.1) | 0 |
| Unspecified diabetes with multiple complications | E14.7 | 1 (0.8) | 0 | 0 | 0 |
| Unspecified diabetes, without complications | E14.9 | 11 (8.3) | 1 (1.8) | 3 (3.4) | 0 |
| Metabolic disorders | E70–E90 | 0 | 1 (1.8) | 36 (41.4) | 1 (12.5) |
| Neuronal ceroid lipofuscinosis | E75.4 | 0 | 1 (1.8) | 0 | 0 |
| Disorders of iron metabolism | E83.1 | 0 | 0 | 1 (1.1) | 0 |
| CF | E84.x | 0 | 0 | 35 (40.2) | 1 (12.5) |
| Mental and behavioral disorders | F01–F99 | 0 | 1 (1.8) | 1 (1.1) | 1 (12.5) |
| Diseases of the nervous system | G00–G98 | 8 (6.0) | 4 (7.3) | 4 (4.6) | 0 |
| Diseases of the circulatory system | I00–I99 | 6 (4.5) | 5 (9.1) | 6 (6.9) | 0 |
| Diseases of the respiratory system | J00–J98 | 2 (1.5) | 2 (3.6) | 2 (2.3) | 0 |
| Diseases of the digestive system | K00–K92 | 0 | 1 (1.8) | 2 (2.3) | 1 (12.5) |
| Diseases of the musculoskeletal system and connective tissue | M00–M99 | 1 (0.8) | 0 | 4 (4.6) | 0 |
| Diseases of the genitourinary system | N00–N98 | 1 (0.8) | 1 (1.8) | 1 (1.1) | 0 |
| Pregnancy, childbirth, and the puerperium | O00–O99 | 0 | 0 | 2 (2.3) | 0 |
| Certain conditions originating in perinatal period | P00–P96 | 1 (0.8) | 0 | 0 | 0 |
| Congenital malformations, deformations, and chromosomal abnormalities | Q00–Q99 | 1 (0.8) | 4 (7.3) | 2 (2.3) | 1 (12.5) |
| Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified | R00–R99 | 2 (1.5) | 0 | 0 | 0 |
| External causes of morbidity and mortality | V00–Y89 | 49 (36.8) | 19 (34.5) | 6 (6.9) | 0 |
| Transport/motor vehicle accident | V00–V99 | 16 (12.0) | 4 (7.3) | 3 (3.4) | 0 |
| Other external causes of accidental injury | W00–X59 | 17 (12.8) | 6 (10.9) | 2 (2.3) | 0 |
| Intentional self-harm | X60–X74 | 13 (9.8) | 2 (3.6) | 1 (1.1) | 0 |
| Assault | X85–Y09 | 1 (0.8) | 5 (9.1) | 0 | 0 |
| Event of undetermined intent | Y10–Y34 | 2 (1.5) | 0 | 0 | 0 |
| Complications of medical/surgical care | Y40–Y84 | 0 | 1 (1.8) | 0 | 0 |
| Sequelae of external causes of morbidity and mortality | Y85–Y89 | 0 | 1 (1.8) | 0 | 0 |
| Unknown cause of death reported to study† | Unknown | 3 (2.3) | 2 (3.6) | 0 | 1 (12.5) |
| Contributing cause of death | |||||
| Diabetes | E00–E14 | 14 (10.5) | 7 (12.7) | 10 (11.5) | 2 (25.0) |
*
All eight of these decedents had their type classified as unknown. None were classified as having monogenic or hybrid diabetes type.
†
Reported as deceased by the family or medical care providers but were not matched in the NDI search due to nonlinkage with the NDI.