Table 1. Characteristics of Included Studies.
Study (location) | Period | Setting | Recruitment | Follow-up | Dementia | Mortality | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Sample | Response rate, % | Included or excluded individuals | Source of outcome data | Assessment | Maximum follow-up time, y | Diagnosis | Lost to follow-up, % | Maximum follow-up time, y | Verification | |||
ZARADEMP (Zaragoza, Spain)16 | 1994-1999 | Community dwelling and institutionalized | Random census sample stratified by age and sex | 79 | Included: aged ≥55 y | Follow-up cognitive screening and municipal death registry | Every 2 y | 4 | Psychiatrist-confirmed DSM-IV diagnosisa | 10 | 13 | Verified by death records |
SNAC-K (Stockholm, Sweden)17 | 2001-2020 | Community dwelling and institutionalized | Random population sample stratified by age; multiple cohorts | 73 | Included: aged ≥60 y | Follow-up cognitive screening, medical registries, informant interviews, and death certificates |
|
12 | 2nd independent physician–confirmed DSM-III-R diagnosis | 11 | 16 | Verified by death records |
Kungsholmen Project (Stockholm, Sweden)18 | 1987-1996 | Community dwelling and institutionalized | Kungsholmen district (75+) | 76 | Included: aged ≥75 y | Follow-up cognitive screening, medical registries, informant interviews, and death certificates | Every 3 y | 9 | 2nd independent physician–confirmed DSM-III-R diagnosis | 12 | 11 | Verified by death records |
LEILA 75+ (Leipzig, Germany)19 | 1997-2014 | Community dwelling and institutionalized | Representative population sample | 75 | Included: aged ≥75 y | Follow-up cognitive screening, death certificates, and relative interviews | Every 1.5 y | 16 | Expert panel–confirmed DSM-III-R or DSM-IV diagnosis | 9 | 16 | Verified by death records |
H70 (Gothenburg, Sweden)20 | 2000-2012 | Community dwelling and institutionalized | Representative population samples; 1930 cohorts | 72 | Included: aged 70, 75, and 79 y | Follow-up cognitive screening, medical registries, informant interviews, and death records | Every 5 y | 12 | DSM-III-R diagnosis | 0 | 12 | Verified by death records |
PreDIVA (Amsterdam, the Netherlands)21 | 2006-2015 | Community dwelling only | General practice populations (>98% Dutch population is registered with a general practitioner) | 53 |
|
Follow-up cognitive screening, EHRs, and municipal death records | Every 2 y | 9 | Expert panel–confirmed DSM-IV diagnosis | 2 | 9 | Verified by death records |
ACT (Seattle, Washington)22 | 1994-2020 | Community dwelling only | Random health insurance sample (representative of local population) | 48 |
|
Follow-up cognitive screening, medical records, and death certificates | Every 2 y | 25 | Expert panel–confirmed DSM-IV diagnosis | 3 | 25 | Verified by death records |
Abbreviations: ACT, Adult Changes in Thought; DSM-III-R, Diagnostic and Statistical Manual of Mental Disorders (Third Edition Revised); DSM-IV, Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition); EHR, electronic health record; H70, Gothenburg H70 Birth Cohort Study; LEILA 75+, Leipzig Longitudinal Study of the Aged; PreDIVA, Prevention of Dementia by Intensive Vascular Care; SNAC-K, Swedish National Study of Aging and Care in Kungsholmen; ZARADEMP, Zaragoza Dementia Depression Project.
No dementia information was available for individuals between last assessment and death or study dropout.