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. 2021 Nov 30;9:780023. doi: 10.3389/fcell.2021.780023

TABLE 2.

Mutations of SRSF6 gene in cancers according to cBioPortal online TCGA cancer database.

Type of cancer Alteration Frequency (%)
Missense_mutation Nonsense_mutation Frameshift mutation In frame deletion Splice site Fusion gene
Colorectal adenocarcinoma 1.18 0.5 0.34 0 0 0.17
Stomach adenocarcinoma 1.59 0 0.23 0 0.23 0
Uterine corpus endometrial carcinoma 3.59 1.13 0 0.19 0 0
Bladder urothelial carcinoma 1 0 0 0 0 0
Esophageal adenocarcinoma 1.1 0 0 0 0 0
Skin cutaneous melanoma 1.35 0.22 0 0 0.22 0
Lung adenocarcinoma 1.06 0 0 0 0 0
Cervical squamous cell carcinoma 0.67 0.34 0 0 0 0
Head and neck squamous cell carcinoma 0.96 0 0 0.19 0 0
Lung squamous cell carcinoma 0.41 0 0 0 0.2 0
Pancreatic adenocarcinoma 1.09 0 0 0 0 0
Kidney renal papillary cell carcinoma 1.06 0 0 0 0 0
Acute myeloid leukemia 0.5 0 0 0 0 0
Liver hepatocellular carcinoma 0.54 0 0 0 0 0
Glioblastoma multiforme 0.34 0 0 0 0 0
Brain lower grade glioma 0.2 0 0 0 0 0