Table 2. Activity of 15–34 on TLX in the VP16/TLX Setting^a.

^aCompounds were tested to a maximum concentration of 30 μM. Fold repression refers to the maximum fold increase in reporter activity (compared to 0.1% DMSO) resulting from the inhibition of TLX. Control experiments on Gal4-VP16 in the absence of Gal4-TLX have excluded non-specific effects and confirmed TLX-mediated activity for all active compounds. All data are mean ± SEM, n ≥ 3.