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. 2021 Dec 1;4(6):1849–1866. doi: 10.1021/acsptsci.1c00226

Table 3. The 11 Compounds’ IC₅₀ over Cell Proliferation of MDA-MB-231, iHMEC, MCF10A, and SKBR3.

	MCF10-A		iHMEC		MDA-MB-231		SKBR-3
Cpd	IC₅₀ (μM) [95% CI]	R²	IC₅₀ (μM) [95% CI]	R²	IC₅₀ (μM) [95% CI]	R²	IC₅₀ (μM) [95% CI]	R²
C1	1.8 [1.7–2.0]	0.99	11 [very wide]	0.98	1.8 [1.7–1.9]	0.99	2.5 [2.2–2.9]	0.99
C2	15 [12–19]	0.94	21 [15–30]	0.96	61 [56–66]	0.96	62 [56–68]	0.96
C3	62 [60–64]	0.98	4.1 [2.7–6.4]	0.96	62 [60–64]	0.98	65 [62–69]	0.98
C4	56 [38–92]	0.97	27 [21–36]	0.98	59 [57–60]	0.98	47 [45–50]	0.99
C5	40 [38–42]	0.98	57 [14–211]	0.97	42 [41–43]	0.99	63 [59–67]	0.99
C6a	100 [92–110]	0.99	62 [44–87]	0.98	38 [36–39]	0.99	52 [50–54]	0.99
C6b	21 [19–24]	0.98	58 [49–69]	0.99	63 [61–64]	0.99	43 [42–45]	0.99
C7	203 [143–286]	0.96	15 [6–35]	0.95	100 [94–106]	0.99	259 [106–633]	0.92
C8	88 [80–96]	0.97	9 [5–16]	0.98	104 [96–112]	0.99	116 [102–132]	0.91
C9	7 [6–9]	0.99	>100		7.9 [7.6–8.1]	0.99	9.8 [9.4–10.1]	0.99
C10	10 [8–13]	0.97	9 [8–10]	0.99	11.7 [11.3–12.1]	0.99	22 [21–23]	0.99
BPTES	12 [11–13]	0.97	>100		1.4 [1.2–1.0]	0.99	26 [17–40]	0.87