Table 1. List of Metabolic Parameters Measured in Male Mice after 11 Weeks of HFD ± XP/XNa.
| HFD | HFD + XP | HFD + XN | |
|---|---|---|---|
| Final body weight (g) | 40.42 ± 1.94 | 37.87 ± 1.72 | 44.25 ± 1.97 |
| Fasting glucose (mg/dL) | 120.39 ± 13.50 | 128.98 ± 7.18 | 142.67 ± 6.29 |
| Insulin (μU/mL) | 77.71 ± 29.15 | 34.36 ± 3.73 | 71.17 ± 34.38 |
| HOMA-IR | 49.56 ± 18.19 | 10.94* ±1.52 | 26.76 ± 13.47 |
| AST (U/mL) | 0.45 ± 0.13 | 0.30 ± 0.06 | 0.16 ± 0.03 |
| ALT (U/mL) | 0.55 ± 0.22 | 0.38 ± 0.07 | 0.22 ± 0.06 |
| MCP1 (pg/mL) | 69.20 ± 14.07 | 45.00 ± 4.68 | 57.34 ± 15.74 |
| IL-6 (pg/mL) | 1.43 ± 0.53 | 5.78 ± 2.04 | 5.03 ± 3.3 |
| PCSK9 (ng/mL) | 211 ± 15.80 | 217.166 ± 26.88 | 215 ± 35.12 |
| Plasma TG (mg/dL) | 87.39 ± 13.17 | 81.81 ± 4.33 | 173.13** ± 23.24 |
| Plasma cholesterol (mg/dL) | 175.56 ± 5.70 | 160.47 ± 4.73 | 170.88 ± 6.76 |
a
Data displayed as mean ± SEM (n = 4–8 per group). Significant differences are marked as *p < 0.05, **p < 0.01, and ***p < 0.001 for the effect of treatment, one-way ANOVA.