Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 30;12:774776. doi: 10.3389/fimmu.2021.774776

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Qiu, Hua, Li, Zhou and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

COVID-19 patients were characterized by upregulated m⁶A genes and activation of the lymphocytes. (A) The expression of 20 m⁶A genes of blood leukocytes between patients with or without COVID-19. (B) Correlation plot of 20 m⁶A genes. The positive correlation was marked with blue, and negative correlation was marked with red. The size of circle represents the absolute value of correlation coefficients. (C) GSVA enrichment analysis showing activated interferon pathways in COVID-19 patients. Red represents high expression, blue represents low expression. (D) The abundance of leukocytes in patients with or without COVID-19. (E) The significant leukocytes fractions in patients with or without COVID-19. (F) The heatmap of correlation between leukocytes and m⁶A genes. The positive correlation was marked with blue, and negative correlation was marked with red. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, no significance.