FIGURE 4.

Estimation of the non-linear effect on 28-day fatality ratio using a generalised additive model in patients with severe coronavirus disease 2019 (COVID-19) stratified by intensive care unit (ICU) admission. a) Age is shown to be an essential factor for higher fatality ratio in patients with severe COVID-19; however, patients admitted to the ICU have a lower fatality ratio independent of age. Even after adjusting by b) the number of new cases per million at the moment of hospital admission and c) the interaction over time, the marginal 28-day fatality ratio was lower in patients admitted to the ICU.