TABLE 5.

Linear regression analysis to find independent predictors of 6th day tacrolimus C₀/D ratio.

Variable	Coefficient (95% CI)	p Value
Constant	158.74(103.01–214.46)	<0.001 a
Age	−0.36(−1.41–0.69)	0.495
Male gender	3.95(−22.19–30.1)	0.764
CYP3A5 a 3	−40.48[−68.12–(−12.83)]	0.005 a
ABCB1 C3435T	−14.48(−40.56–11.59)	0.272
ABCB1 G2677T	12.66(−14–39.34)	0.348
CYP3A4 a 1G	−11.54(−37.41–14.31)	0.377
CYP3A4 a 1B	−14.66(−51.97–22.64)	0.436

R square = 0.353; p value <0.001.

^aStatistically significant.