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. 2021 Nov 30;9:765578. doi: 10.3389/fcell.2021.765578

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Copyright © 2021 Wang, Zhao, Yang, Dong, Lin, He, Cui and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune status among the four subgroups (A) Overall survival for the four CMS (B) Tumor mutation burden among the three subtypes (C) Immune-cell infiltration among the three subtypes (D–F) The immune microenvironment among the three groups.