TABLE 2.
Top three clusters with their representative enriched terms of GO analysis.
| GO | ID | Description | Count | p value | Gene |
|---|---|---|---|---|---|
| BP | GO:0070268 | Cornification | 47 | 4.11E-32 | KRT16/KRT83/PI3/DSG1/DSC2/KRT9/KRT6B/KRT79/TGM1/KRT86/KRT6A/KLK5/DSG3/KRT6C/CASP14/KLK14/SPINK5/DSC3/KRT81/PKP1/TGM5/KRT37/KRT4/SPINK6/KRT34/KRT23/KRT78/KRT5/KRT31/KRT1/KRT3/KRT17/IVL/KRT14/KRT75/KRT35/KRT84/LIPK/KRT85/KRT77/KRT82/SPRR1B/KRT33B/SPRR2G/SPRR2D/SPRR2E/LCE3D |
| BP | GO:0031424 | Keratinization | 53 | 3.39E-22 | KRT16/KRT83/PI3/DSG1/DSC2/KRT9/KRT6B/KRT79/TGM1/KRT86/CDH3/KRT6A/KLK5/DSG3/KRT6C/CASP14/KLK14/SPINK5/DSC3/KRT81/PKP1/TGM5/KRT37/KRT4/SPINK6/KRT34/KRT23/KRT78/KRT5/KRT31/KRT1/KRT3/KRT17/IVL/KRT14/KRT75/KRT35/KRT84/KRTAP3-3/LIPK/KRT85/KRT77/KRT82/KRTAP1-1/LCE3A/SPRR1B/KRT33B/SPRR2G/SPRR2D/SPRR2E/LCE3D/SPRR4/KRTAP4-1 |
| BP | GO:0043588 | Skin development | 70 | 1.12E-19 | FOXC1/FGF10/KRT16/KRT83/PI3/DSG1/DSC2/EGFR/CTSV/KRT9/KRT6B/GAL/KRT79/TGM1/KRT86/CDH3/KRT6A/KLK5/FERMT1/CLDN1/SCEL/GJB3/DSG3/KRT6C/FOXQ1/CASP14/LHX2/KLK14/SOSTDC1/SPINK5/LGR5/DSC3/EDAR/KRT81/DKK1/PKP1/TGM5/KRT37/KRT4/SPINK6/KRT34/KRT23/KRT78/KRT5/KRT31/KRT1/KRT3/KRT17/IVL/KRT14/KRT75/KRT35/KRT84/KRTAP3-3/LIPK/KRT85/KRT77/KRT82/S100A7/KRTAP1-1/LCE3A/SPRR1B/KRT33B/SPRR2G/SPRR2D/SERPINB13/SPRR2E/LCE3D/SPRR4/KRTAP4-1 |
| CC | GO:0045095 | Keratin filament | 22 | 8.00E-10 | KRT83/KRT6B/KRT79/KRT86/KRT6A/KRT6C/CASP14/KRT81/KRT4/KRT78/KRT5/KRT1/KRT3/KRT14/KRT75/KRT84/KRTAP3-3/KRT85/KRT77/KRT82/KRTAP1-1/KRTAP4-1 |
| CC | GO:0005882 | intermediate filament | 34 | 1.23E-09 | INA/KRT16/KRT83/KRT9/KRT6B/KRT79/KRT86/KRT6A/KRT6C/KRT222/CASP14/KRT81/PKP1/KRT37/KRT4/KRT34/KRT23/KRT78/KRT5/KRT31/KRT1/KRT3/KRT17/KRT14/KRT75/KRT35/KRT84/KRTAP3-3/KRT85/KRT77/KRT82/KRTAP1-1/KRT33B/KRTAP4-1 |
| CC | GO:0045111 | Intermediate filament cytoskeleton | 36 | 6.84E-09 | INA/KRT16/KRT83/KRT9/KRT6B/KRT79/SLC1A6/KRT86/KRT6A/S100A8/KRT6C/KRT222/CASP14/KRT81/PKP1/KRT37/KRT4/KRT34/KRT23/KRT78/KRT5/KRT31/KRT1/KRT3/KRT17/KRT14/KRT75/KRT35/KRT84/KRTAP3-3/KRT85/KRT77/KRT82/KRTAP1-1/KRT33B/KRTAP4-1 |
| MF | GO:0030414 | Peptidase inhibitor activity | 31 | 3.30E-09 | A2ML1/RARRES1/PI3/SLPI/NLRP7/CST9L/SERPINB7/CST5/SERPINB5/SPINK5/CST2/CARD17/UMODL1/HMSD/CST9/SPINK6/SERPINB2/SERPINB4/SERPINA11/SERPINB12/MT3/CST4/CARD18/FETUB/SMR3B/SERPINA6/SERPINB3/OPRPN/SMR3A/SERPINB13/CSN2 |
| MF | GO:0015267 | Channel activity | 56 | 4.50E-09 | SLC26A9/TRPM8/TTYH1/TMC3/GRIA1/KCNS1/KCNQ4/KCNK5/KCNG1/CLCN4/KCNB2/CHRNA9/GABRP/GRIA2/KCNE4/GABRA5/CHRNA5/HTR3A/GABRE/CNGB1/GJB3/KCNE5/KCNK9/CNGA1/GRIN2B/CACNA1B/TRPV3/GLRA3/SCN7A/TRPV6/CNGA3/KCNH1/GJB7/KCNC1/AQP5/ABCC8/KCNJ4/CLIC6/KCNC2/GABRG3/GABRQ/KCNV1/KCNF1/UNC80/GJB4/CLCA2/ASIC2/OTOP1/KCNJ3/CACNG5/GABRA3/KCNJ18/KCNK16/AQP12B/HTR3B/CLCA1 |
| MF | GO:0022803 | Passive transmembrane transporter activity | 56 | 4.86E-09 | SLC26A9/TRPM8/TTYH1/TMC3/GRIA1/KCNS1/KCNQ4/KCNK5/KCNG1/CLCN4/KCNB2/CHRNA9/GABRP/GRIA2/KCNE4/GABRA5/CHRNA5/HTR3A/GABRE/CNGB1/GJB3/KCNE5/KCNK9/CNGA1/GRIN2B/CACNA1B/TRPV3/GLRA3/SCN7A/TRPV6/CNGA3/KCNH1/GJB7/KCNC1/AQP5/ABCC8/KCNJ4/CLIC6/KCNC2/GABRG3/GABRQ/KCNV1/KCNF1/UNC80/GJB4/CLCA2/ASIC2/OTOP1/KCNJ3/CACNG5/GABRA3/KCNJ18/KCNK16/AQP12B/HTR3B/CLCA1 |