TABLE 1.
Demographics and Clinical Characteristics Among Pediatric Coronavirus Disease 2019 Patients and Comparison of ICU Versus Non-ICU Admissions
| Category and Subcategory | Total (N = 874) | Non-ICU (N = 470) | ICU (N = 404) | p |
|---|---|---|---|---|
| Age (yr), median (interquartile range) | 8 (1.25–14) | 5.67 (0.74–13.7) | 10.0 (3.0–15.0) | < 0.01 |
| Neonate, n (%) | 36 (4.1) | 25 (5.3) | 11 (2.7) | < 0.01 |
| Infant, n (%) | 217 (24.7) | 146 (31.0) | 71 (17.6) | |
| Child, n (%) | 296 (33.7) | 144 (30.6) | 152 (37.6) | |
| Adolescent, n (%) | 325 (37.2) | 155 (32.9) | 170 (42.1) | |
| Sex (males), n (%) | 473 (54.1) | 252 (53.6) | 221 (54.7) | 0.78 |
| Race, n (%) | ||||
| White | 379 (43.3) | 210 (45.2) | 169 (41.8) | 0.53 |
| Black | 212 (25.8) | 105 (22.6) | 107 (26.5) | |
| Othera | 230 (26.4) | 122 (26.2) | 108 (26.7) | |
| Unknown | 53 (6.1) | 27 (5.8) | 20 (4.9) | |
| Symptoms, n (%) | ||||
| Fever | 586 (67.0) | 307 (65.2) | 279 (69.1) | 0.25 |
| Nausea, vomiting | 296 (33.9) | 132 (28.0) | 164 (40.6) | < 0.01 |
| Cough | 264 (30.2) | 135 (28.7) | 129 (31.9) | 0.33 |
| Abdominal pain | 211 (24.1) | 93 (19.7) | 118 (29.1) | < 0.01 |
| Myalgia/fatigue | 186 (21.3) | 80 (17.0) | 106 (26.2) | < 0.01 |
| Dyspnea | 183 (20.9) | 67 (14.2) | 116 (28.7) | < 0.01 |
| One symptom | 144 (16.4) | 94 (20) | 50 (12.4) | < 0.01 |
| Two symptoms | 148 (16.9) | 92 (19.5) | 56 (13.9) | 0.03 |
| Three symptoms | 169 (19.3) | 89 (18.9) | 80 (19.8) | 0.73 |
| ≥4 symptoms | 413 (47.2) | 195 (41.4) | 218 (54.0) | < 0.01 |
| Any comorbidity, n (%) | 378 (43.2) | 194 (41.2) | 194 (48.0) | 0.04 |
| ≥2 comorbidities, n (%) | 209 (23.9) | 99 (21.0) | 110 (27.2) | 0.03 |
| Asthma | 101 (11.5) | 44 (9.3) | 57 (14.1) | 0.02 |
| Seizure disorder | 67 (7.6) | 26 (5.5) | 41 (10.2) | 0.01 |
| Obesity | 58 (6.6) | 18 (3.8) | 40 (9.9) | < 0.01 |
| Developmental delay | 57 (6.5) | 24 (5.1) | 33 (8.2) | 0.07 |
| Diabetes | 25 (2.8) | 6 (1.2) | 19 (4.7) | < 0.01 |
| Cerebral palsy | 23 (2.6) | 11 (2.3) | 12 (3.0) | 0.67 |
| Body mass index (N = 817), median (interquartile range) | 19.4 (16.0–25.8) | 18.9 (15.4–24.3) | 20.1 (16.4–28.0) | < 0.01 |
| Underweight, n (%) | 73 (8.9) | 41 (9.6) | 32 (8.2) | 0.05 |
| Normal, n (%) | 336 (41.0) | 186 (43.5) | 150 (38.5) | |
| Overweight, n (%) | 110 (13.4) | 63 (14.7) | 47 (12.1) | |
| Obese, n (%) | 298 (36.5) | 137 (32.0) | 161 (41.2) | |
| Ethnicity (N = 780), n (%) | ||||
| Non-Hispanic | 492 (62.9) | 255 (60.0) | 237 (66.8) | 0.05 |
| Hispanic | 288 (36.9) | 170 (40.0) | 118 (33.2) | |
| Multisystem inflammatory syndrome in children (N = 838), n (%) | 236 (28.2)b | 65 (14.6) | 173 (43.8) | < 0.01 |
aOther race is represented as Asian-American 13 (1.4%), East Asian 1 (0.1%), Mixed race 12 (1.3%), Native Hawaiian or Pacific Islander 4 (0.4%), other 161 (18.5%), South Asian 31 (3.5%), Southeast Asian 3 (0.3%), West Asian 5 (0.5%), unknown 47 (5.4%). Missing race in six patients. Body mass index missing in 57 patients. Multisystem inflammatory syndrome in children (MIS-C) categorization only available in 838 patients.
bOf 236 patients with MIS-C, 234 had coronavirus disease 2019 (COVID-19) immunoglobulin G (IgG) levels done, 138 of 234 were positive for COVID-19 IgG.
Six most common signs and symptoms and six most common comorbidities are presented. Obesity in the comorbidities section (physician defined only).