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. 2021 Nov 30;9:718974. doi: 10.3389/fcell.2021.718974

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Copyright © 2021 Wang, Li, Ming, Wei, Du, Zhou, Zong and Xiao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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m⁶A/m⁵C/m¹A-related mRNA–lncRNA co-expression network and identification of prognostic value of m⁶A/m⁵C/m¹A-related lncRNAs. (A) 147 lncRNAs co-expressed with m⁶A/m⁵C/m¹A-related genes. Green represents lncRNAs, while red represents m⁶A/m⁵C/m¹A-related genes. (B) The forest plot of univariate Cox regression showed that 44 lncRNAs with prognostic value were protective factors of HNSCC. (C,D) The heatmap and boxplot of differential expression of 44 lncRNAs with prognostic value between 44 normal tissues and 501 tumor tissues in TCGA-HNSCC database.