Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Binding affinity of compound 2, 3 and 4 with SARS-CoV-2 3CLpro determined by MRMS and the inhibition of 3CLpro by the three compounds.
| ID | Name | IC50 (μM) | Kd (μM) | Bmax |
|---|---|---|---|---|
| 2 | Baicalein | 0.94 ± 0.20 | 1.43 ± 0.15 | 1.02 ± 0.02 |
| 3 | Scutellarein | 3.02 ± 0.11 | 3.85 ± 0.47 | 0.88 ± 0.02 |
| 4 | Ganhuangenin | 0.84 ± 0.06 | 1.09 ± 0.14 | 1.11 ± 0.01 |
