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In vivo anti-metastatic effect. a Body weight change during treatment. b Representative photographs of excised lungs and c nodule numbers. d H&E staining of lung sections in each group. Scale bar, 50 μm. Significance criteria: *P < 0.05, **P < 0.01. e Excised tumor photographs of orthotopic tumor model. The red circle represents the primary tumor, while the blue arrow represents the site of metastatic tumors. f H&E staining of colon. Scale bar, 100 μm
