TABLE 1.
Metabolic characteristics of wild-type and VAMP3 null micea
| Mice | Concn in serum
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Glucose (mg/dl, n = 9)
|
Insulin (ng/ml, n = 9)
|
Triglycerides (mg/dl, n = 7)
|
Free fatty acids (mM, n = 7)
|
Cholesterol (mg/dl, n = 7)
|
||||||
| Fed | Fasted | Fed | Fasted | Fed | Fasted | Fed | Fasted | Fed | Fasted | |
| Wild type | 158 ± 10 | 110 ± 8 | 1.92 ± 0.29 | 0.38 ± 0.07 | 130.2 ± 16 | 88.1 ± 13 | 0.42 ± 0.04 | 0.57 ± 0.06 | 42.2 ± 5 | 38.8 ± 6 |
| VAMP3 null | 164 ± 12 | 104 ± 7 | 1.71 ± 0.34 | 0.44 ± 0.09 | 138.8 ± 19 | 81.7 ± 12 | 0.46 ± 0.04 | 0.63 ± 0.08 | 50.2 ± 6 | 45.5 ± 7 |
a
Serum was collected from fed or fasted wild-type or VAMP3 null mice (14 to 16 weeks of age), and the indicated metabolic parameters were determined.