TABLE 1.
Comparison of demographic and clinical characteristics by the neutrophil to lymphocyte ratio (NLR).
| Overall (n = 1,648) | NLR below median (n = 826) | NLR above median (n = 822) | P-value | |
| Age, median [Q1, Q3] | 69.0 [64.0, 76.0] | 68.0 [63.0, 74.0] | 71.0 [65.0, 77.0] | <0.001 |
| Female sex, n (%) | 920 (55.8) | 515 (62.3) | 405 (49.3) | <0.001 |
| BMI, median [Q1, Q3] | 27.7 [24.7, 30.9] | 27.5 [24.3, 30.5] | 28.0 [25.1, 31.4] | 0.006 |
| LDL cholesterol, median [Q1, Q3] | 96.0 [78.0, 118.0] | 101.5 [81.0, 122.0] | 93.0 [75.0, 112.0] | <0.001 |
| HDL cholesterol, median [Q1, Q3] | 60.0 [49.0, 74.0] | 61.0 [50.0, 76.0] | 58.0 [47.0, 71.0] | <0.001 |
| Total cholesterol, median [Q1, Q3] | 183.0 [158.8, 207.0] | 188.0 [163.2, 211.0] | 177.0 [153.0, 202.0] | <0.001 |
| Triglycerides, median [Q1, Q3] | 99.0 [74.0, 133.0] | 96.0 [72.0, 132.0] | 100.5 [76.0, 134.0] | 0.041 |
| Smoker, n (%) | 78 (4.7) | 32 (3.9) | 46 (5.6) | 0.126 |
| Diabetes, n (%) | 159 (9.6) | 76 (9.2) | 83 (10.1) | 0.594 |
| Systolic BP, median [Q1, Q3] | 125.0 [115.0, 137.0] | 125.0 [113.0, 136.0] | 126.0 [116.0, 137.0] | 0.011 |
| Diastolic BP, median [Q1, Q3] | 72.0 [65.0, 78.0] | 72.0 [66.0, 78.0] | 71.0 [65.0, 78.0] | 0.176 |
| CVD History, n (%) | 295 (17.9) | 122 (14.8) | 173 (21.0) | 0.001 |
| NLR, median [Q1, Q3] | 2.3 [1.8, 3.0] | 1.8 [1.4, 2.0] | 3.0 [2.6, 3.8] | <0.001 |
| Number of dementia cases, n (%) | 51 (3.1) | 16 (1.9) | 35 (4.3) | 0.01 |
| Number of deaths, n (%) | 92 (5.6) | 33 (4.0) | 59 (7.2) | 0.007 |
BMI, body mass index; BP, blood pressure; LDL, low-density lipoprotein; HDL, high-density lipoprotein; Chol, cholesterol; CVD history, history of cardiovascular events. Definitions described in section “Materials and Methods.”