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. 2021 Dec 7;8(6):ENEURO.0341-21.2021. doi: 10.1523/ENEURO.0341-21.2021

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Copyright © 2021 Hathaway et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 4. — Effects of intra-lOFC infusions of the 5-HT_2C receptor agonist RS 102221 in (A) risk-preferring animals (n = 9) and (B) optimal decision-makers (n = 9) on P1–P4 choice. Antagonism of the 5-HT_2C receptor in the lOFC decreased P3 choice and increased P1 choice on the crGT in risk-preferring rats. Data are expressed as mean ± SEM; *p < 0.05 compared with vehicle.