Table 2. Adjudicated phenotypes and etiologies.
| Etiology | Number of Subjects |
|---|---|
| Bacterial Infection | |
| Streptococcus pyogenes | 11 |
| Streptococcus pneumoniae | 9 |
| Staphylococcus aureus | 7 |
| Haemophilus influenzae | 2 |
| Legionella pneumophila | 2 |
| Pseudomonas aeruginosa | 2 |
| Othera | 14 |
| Viral Infection | |
| Influenza A | 78 |
| RSV | 12 |
| Metapneumovirus | 12 |
| Rhinovirus | 11 |
| Enterovirus/Rhinovirus | 11 |
| Coxsackievirus/Echovirus | 8 |
| Coxsackievirus/Echovirus + Rhinovirus | 8 |
| Coronavirus (not SARS-CoV-2) | 6 |
| Parainfluenza | 6 |
| Influenza B | 4 |
| Adenovirus | 4 |
| Epstein Barr Virus | 2 |
| Non-Infectious Illness | |
| Asthma | 15 |
| Congestive Heart Failure | 15 |
| Interstitial Lung Disease | 6 |
| Pulmonary Embolism | 6 |
| Chronic Obstructive Pulmonary Disease | 5 |
| Malignancy | 5 |
| Allergic Rhinitis | 3 |
| Chest Pain | 2 |
| Diabetic Ketoacidosis | 2 |
| Myocardial Infarction | 2 |
| Otherb | 16 |
aOther bacterial etiologies included one instance of each of the following: Beta hemolytic Streptococcus (not Group A), Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Pasteurella multocida, Pseudomonas aeruginosa and Alcaligenes xylosoxidans, Staphylococcus aureus and Haemophilus influenzae, Staphylococcus aureus and Pseudomonas aeruginosa, Staphylococcus hominis, Streptococcus agalactiae and Coagulase negative Staphylococcus, Streptococcus anginosus, Streptococcus Group C, Streptococcus pneumoniae and Staphylococcus aureus, and Viridans Group Streptococcus.
bOther non-infectious etiologies included one instance of each of the following: acute allograft rejection, acute respiratory distress syndrome, anaphylaxis, hemidiaphragm paralysis, hemoptysis, intoxication, malignant pleural effusion, migraine, nephrolithiasis, post-infectious cough, post-operative pain, post-operative vocal cord paralysis, pulmonary hypertension, subglottic papilloma, syncope, tracheobronchomalacia.