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. Author manuscript; available in PMC: 2021 Dec 14.
Published in final edited form as: Cell Rep. 2021 Aug 10;36(6):109517. doi: 10.1016/j.celrep.2021.109517

Figure 3. Direct LIN28B binding and LIN28B-dependent changes in gene expression are uncorrelated.

Figure 3.

(A) Scatterplot showing that total mapped reads per transcript normalized for abundance (normalized eCLIP RPM) is uncorrelated to the fold change in polysome enrichment per transcript, at LIN28 expression level [X4] compared with control HEK293 that do not express LIN28B.

(B) The same dataset plotted in (A) but split into gene sets that are bound or not bound by LIN28B and plotted as distributions relative to the fold change polysome enrichment per transcript at LIN28B expression level [X4] compared with control HEK293 that do not express LIN28B.