1. Analyses of heterogeneity.

Analyses	Number of studies (participants)	Sensitivity (95% CI)	Specificity (95% CI)	P value%
Overall	58 (7462)	0.95 (0.94 to 0.97)	0.96 (0.95 to 0.97)	‐
MRI protocol ‐ field of view whole abdomen limited area	16 (1944) 13 (1326)	0.95 (0.93 to 0.97) 0.97 (0.94 to 0.99)	0.96 (0.90 to 0.99) 0.93 (0.87 to 0.96)	LR Chi2 = 2.37 P = 0.31
Slice thickness =< 4 mm > 4 mm	8 (1944) 24 (2380)	0.97 (0.93 to 0.99) 0.96 (0.94 to 0.97)	0.95 (0.84 to 0.98) 0.96 (0.93 to 0.98)	LR Chi2 = 1.58 P = 0.45
MRI sequence T2‐weighted images only other	14 (1639) 36 (4788)	0.96 (0.93 to 0.97) 0.96 (0.94 to 0.97)	0.97 (0.95 to 0.98) 0.95 (0.93 to 0.97)	LR Chi2 = 1.16 P = 0.56
Total scan time =< 10 min > 10 min	5 (307) 26 (3144)	0.94 (0.90 to 0.97) 0.96 (0.94 to 0.97)	0.93 (0.85 to 0.96) 0.96 (0.94 to 0.98)	LR Chi2 = 0.42 P = 0.81
Contrast enhancement intravenous or oral contrast no contrast	10 (1252) 41 (5767)	0.97 (0.94 to 0.98) 0.95 (0.92 to 0.97)	0.95 (0.92 to 0.97) 0.97 (0.94 to 0.98)	LR Chi2 = 1.64 P = 0.44

Abbreviations: MRI: magnetic resonance imaging, LR: likelihood ratio

All models fitted with equal variances for the random effects for logit(SN) and logit(SP) in the two groups.