Study	Reason for exclusion
Abdeen 2019	Target condition not appendicitis
Ali 2011	Not diagnostic test accuracy study
Al‐Katib 2016	Not diagnostic accuracy test study, character of cut‐off and cut‐off contingent on non‐visualisation
Armstrong 2011	Not diagnostic test accuracy study
Aronberg 2017	Insufficient data for 2 x 2 table
Bernbeck 2015	Insufficient data for 2 x 2 table
Birjawi 2009	Not diagnostic test accuracy study
Bracken 2018	Duplicate data: Repplinger 2018 included
Brandon 2015	Not index test
Brian 2017	Not diagnostic test accuracy study
Brook 2007	Case report
Byott 2016	Insufficient data for 2 x 2 table (no response from authors to email seeking missing data)
Cantineau 2009	Case report
Church 2016	Retrospective examination of scans after appendicectomy for appendicitis
Claudius 2015	Duplicate data: Kearl 2016 included
Cobben 2009a	Not diagnostic test accuracy study
Corkum 2017	Duplicate data: Corkum 2018 included
Dabir 2010	Case report
Díaz 2008	Case report
Dibble 2016	Insufficient data for 2 x 2 table
Dibble 2018	Duplicate data: Dibble 2017 included
Dillman 2015	Duplicate data: Dillman 2016 included
Epifanio 2016	Insufficient data for 2 x 2 table
Gottgens 2014	Insufficient information for 2 x 2 table
Harringa 2016	Duplicate data of Kinner 2017
Harringa 2019	Target condition not appendicitis
Herliczek 2012	Duplicate data: Herliczek 2013 included
Hormann 2002	Not target condition
How 2014	Case report
Hutton 2015	Case report
Inci 2011a	Duplicate data: Inci 2011 included
Inoue 2020	Target condition not appendicitis
Kearl 2014	Duplicate data: Kearl 2016 included
Kelly 2017	Insufficient data for 2 x 2 table
Koning 2014a	Duplicate data: Koning 2014 included
Koning 2014b	Duplicate data: Koning 2014 included
Kruger 2019	Not diagnostic test accuracy study
Leeuwenburgh 2013	Duplicate data: Leeuwenburgh 2014 included
Lescheid 2015	Not diagnostic test accuracy study
Long 2011	Not diagnostic test accuracy study
Lyons 2017	Not diagnostic test accuracy study
Martin 2016	Insufficient data for 2 x 2 table
Meesa 2011a	Duplicate data: Meesa 2011 included
Mittal 2019	Not diagnostic test accuracy study
Modgil 2006	Case report
Naz 2018	Not diagnostic test accuracy study
Nitta 2005a	Not diagnostic test accuracy study
Olympia 2016	Not diagnostic test accuracy study
Orth 2013	Duplicate data: Orth 2014 included
Oto 2009	Not diagnostic test accuracy study
Pedrosa 2009a	Duplicate data: Repplinger 2018 included
Repplinger 2014	Duplicate data: Repplinger 2018 included
Repplinger 2015	Insufficient information for 2 x 2 table
Rosenbaum 2017	Not diagnostic test accuracy study
Saunders 2016	Letter
Shin 2018	Duplicate data: Shin 2017 included
Singh 2007	Not diagnostic test accuracy study
Spalluto 2012	Case report
Steinkeler 2008	Case report
Steinkeler 2017	Not diagnostic test accuracy study
Stiefelhagen 2009	Case report
Stoker 2008	Leading article
Theilen 2014	No reference standard
Thompson 2015	Insufficient information for 2 x 2 table
Trout 2015	No reference standard
Tseng 2018	Not diagnostic test accuracy study
Warner 2020	Not diagnostic test accuracy study
Wolfe 2007	Not diagnostic test accuracy study