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. 2021 Dec 7;2021:4963346. doi: 10.1155/2021/4963346

Table 2.

The role of patented drugs from Chinese herbs in the regulation of ER stress in myocardial I/R.

Patented drugs Experimental models Effects Mechanisms References
Qishen granule OGD/R in H9c2 cells Apoptosis↓, ER stress↓ Bcl-2/BAX↑, caspases-3/12↓, IRE1-CryAB↑ [161]
Shuxuening injection I/R injury in rats Oxidative damage↓, inflammation↓, ER stress↓ CK↓, LDH↓, cTnI↓, MDA↓, SOD↑, GSH-Px↑, CAT↑, GRP78↓, CRT↓, CHOP↓, caspase-12↓, TLR4/NF-κB↓ [162]