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. 2021 Dec 1;44(6):205. doi: 10.18773/austprescr.2021.062

Table 3. Top 10 PBS/RPBS drugs by cost to government (does not include rebates).

Drug Cost to government Prescriptions
1. aflibercept $443,729,600 364,846
2. pembrolizumab $431,701,955 49,694
3. nivolumab $402,113,073 50,593
4. adalimumab $297,594,138 274,986
5. denosumab $263,487,070 963,893
6. apixaban $248,455,067 3,020,507
7. ustekinumab $246,990,067 35,554
8. ranibizumab $221,730,401 190,316
9. lenalidomide $221,365,364 40,554
10. ocrelizumab $175,644,997 10,108