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. 2021 Nov 30;14:752838. doi: 10.3389/fnmol.2021.752838

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Copyright © 2021 Wang, Zhou, Li, Li, Guo and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Diagram of the experimental design. Groups V+S and D+S were operated on 7 days after intracerebroventricular injection. Behavioral tests 1, 2, and 3 weeks after the surgery, including a series of tests, started on days 2, 9, or 16 and lasted for 5 days. Rats were sacrificed 1 day after the last behavioral tests in the 1st and 3rd week after the surgery.