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. 2021 Nov 26;9:1–11. doi: 10.1016/j.toxrep.2021.11.017

Fig. 1.

Fig. 1

Two definitions of the PAS Domain: A: Representation of the founding PER-ARNT-SIM proteins and the boundary of the larger ∼250-300 amino acid domain as originally described [64,65,182]. Schematic maps of the PER-ARNT-SIM proteins with the bHLH domains in black. B: Representation of a generic PAS protein with the PAS domain represented as repeats, PAS-A and PAS-B of approximately 100 amino acids each.