. 2021 Dec 1;11:759595. doi: 10.3389/fonc.2021.759595

Table 7.

Comparison of low-density lipoprotein cholesterol (LDL-C) level at different time-points over the course of treatment.

Group	Baseline	3 months	6 months	9 months	12 months	18 months	24 months	36 months	48 months	60 months
TAM+OFS group	2.56 ± 0.63	2.60 ± 0.75	2.53 ± 0.75	2.36 ± 0.63^#	2.39 ± 0.67	2.54 ± 0.72	2.54 ± 0.74	2.42 ± 0.57	2.53 ± 0.67	2.78 ± 0.69^#
(n)	(81)	(56)	(51)	(39)	(64)	(52)	(59)	(48)	(39)	(23)
TAM group	2.69 ± 0.67	2.66 ± 0.58	2.63 ± 0.73	2.57 ± 0.60*	2.51 ± 0.62	2.63 ± 0.56	2.64 ± 0.67	2.62 ± 0.62*	2.91 ± 0.84*^#	2.74 ± 0.66
(n)	(61)	(48)	(42)	(38)	(49)	(42)	(50)	(41)	(39)	(29)
F_inter-group=18.179, P _inter-group<0.001;F_intra-group=4.540, P _intra-group=<0.001
TAM group	2.56 ± 0.63	2.60 ± 0.75	2.53 ± 0.75	2.36 ± 0.63^#	2.39 ± 0.67	2.54 ± 0.72	2.54 ± 0.74	2.42 ± 0.57	2.53 ± 0.67	2.78 ± 0.69^#
(n)	(81)	(56)	(51)	(39)	(64)	(52)	(59)	(48)	(39)	(23)
AI+OFS group	2.74 ± 0.61	2.90 ± 0.76*	2.96 ± 0.69*^#	2.88 ± 0.71*	2.95 ± 0.75*^#	3.00 ± 0.82*^#	3.06 ± 0.81*^#	3.21 ± 0.89*#	3.21 ± 0.80*^#	3.28 ± 0.73*^#
(n)	(88)	(74)	(70)	(58)	(76)	(68)	(67)	(58)	(48)	(37)
F_inter-group=288.630, P _inter-group<0.001;F_intra-group=11.172, P _intra-group<0.001
TAM+OFS group	2.69 ± 0.67	2.66 ± 0.58	2.63 ± 0.73	2.57 ± 0.60	2.51 ± 0.62	2.63 ± 0.56	2.64 ± 0.67	2.62 ± 0.62	2.91 ± 0.84^#	2.74 ± 0.66
(n)	(61)	(48)	(42)	(38)	(49)	(42)	(50)	(41)	(39)	(29)
AI+OFS group	2.74 ± 0.61	2.90 ± 0.76*	2.96 ± 0.69*^#	2.88 ± 0.71*^#	2.95 ± 0.75*^#	3.00 ± 0.82*^#	3.06 ± 0.81*^#	3.21 ± 0.89*^#	3.21 ± 0.80*^#	3.28 ± 0.73*^#
(n)	(88)	(74)	(70)	(58)	(76)	(68)	(67)	(58)	(48)	(37)
F_inter-group=105.381, P _inter-group<0.001;F_intra-group=5.512, P _intra-group<0.001

n represents patient number.

*P value < 0.05, compared to the other group at the same time-point.

^#P value < 0.05, compared to the baseline at the same group.