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. 2021 Dec 1;11:570208. doi: 10.3389/fonc.2021.570208

Table 2.

Results of the analysis of the prognostic factors for disease free survival.

Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
SII <0.001 <0.001
Low 1.00 1.00
High 4.304 (3.125 -5.929) 4.530 (3.279 -6.258)
Patient age 0.250
≤40 1.00
>40 0.807 (0.560 -1.163)
ER 0.824
1.00
+ 0.964 (0.699 -1.330)
PR 0.732
1.00
+ 0.947 (0.692 -1.295)
HER2 0.363
1.00
+ 0.820 (0.535 -1.257)
Ki-67 status 0.058
1.00
+ 1.596 (0.983 -2.590)
pT Stage <0.001 <0.001
1 1.00 1.00
2-4 1.340 (1.163 -1.543) 1.368 (1.192 -1.571)
pN Stage 0.024 0.027
1.00 1.00
+ 1.182 (1.022 -1.368) 1.179 (1.019 -1.364)
Histological grade <0.001 0.034
I-II 1.00 1.00
III 1.795 (1.277-2.521) 1.595 (1.036 -2.451)
Surgery type 0.344
Mastectomy 1.00
BCS 1.207 (0.821-1.769)
Chemotherapy 0.08
No 1.00
Yes 1.340 (0.968-1.852)
Radiotherapy 0.121
No 1.00
Yes 0.775 (0.561-1.068)
Hormonal therapy 0.110
No 1.00
Yes 0.767 (0.553-1.060)
Target therapy 0.253
No 1.00
Yes 1.259 (0.851-1.858)