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. 2021 Dec 1;11:570208. doi: 10.3389/fonc.2021.570208

Table 3.

Results of the analysis of the prognostic factors for overall survival.

Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
SII <0.001 <0.001
Low 1.00 1.00
High 4.296 (2.906 -6.350) 3.825 (2.594 -5.640)
Patient age 0.745
≤ 40 1.00
>40 0.927 (0.589 -1.460)
ER 0.187
1.00
+ 0.774 (0.528 -1.133)
PR 0.517
1.00
+ 0.883 (0.605 -1.288)
HER2 0.733
1.00
+ 0.916 (0.552 -1.519)
Ki-67 status 0.112
1.00
+ 1.636 (0.892 -3.000)
pT Stage 0.003 <0.001
1 1.00 1.00
2-4 1.300 (1.093 -1.546) 1.377 (1.162 -1.632)
pN Stage 0.006 0.035
1.00 1.00
+ 1.272 (1.070 -1.512) 1.211 (1.014 -1.447)
Histological grade <0.001 0.006
I-II 1.00 1.00
III 2.058 (1.364-3.101) 1.937 (1.207 -3.106)
Surgery type 0.569
Mastectomy 1.00
BCS 1.147 (0.721-1.820)
Chemotherapy 0.151
Yes 1.00
No 0.752 (0.508-1.109)
Radiotherapy 0.533
Yes 1.00
No 0.885 (0.598-1.305)
Hormonal therapy 0.212
No 1.00
Yes 0.779 (0.525-1.153)
Target therapy 0.405
No 1.00
Yes 1.223 (0.764-1.959)