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. 2021 Dec 1;12:732135. doi: 10.3389/fimmu.2021.732135

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Copyright © 2021 Heipertz, Zynda, Stav-Noraas, Hungler, Boucher, Kaur and Vemuri

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CAR-NK Molecule Delivery of genetic cargo into NK cells with CAR encoding retro (RV), lenti (LV), or adeno-associated (AAV) vectors. CAR molecule is shown on the right side with single-chain variable fragment (scFv including V_H and V_L chains), hinge, transmembrane (TM), and signaling domain. Co-stimulatory signaling domains are indicated in different colors.