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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Int J Drug Policy. 2021 Aug 5;98:103393. doi: 10.1016/j.drugpo.2021.103393

Table 3:

Timeline for emergence of select NPS with respect to online mentions and exposures, as well as US drug scheduling actions.

Drug First Mention
(Reddit)		 First Exposure
(Toxicology)		 Intent to
Schedule (US)		 Temporary
Schedule (US)
Carfentanil 2/2013 10/2016 1/1988 10/1988
U-47700 11/2014 10/2016 9/2016 11/2016
Eutylone 2/2015 5/2019 Not Scheduled
Flualprazolam 8/2015 4/2018 Not Scheduled
N-Ethylpentylone 4/2016 8/2017 6/2018 8/2018
5F-MDMB-PICA 9/2018 6/2018 12/2018 4/2019
Isotonitazene 1/2019 11/2019 6/2020 8/2020
Brorphine 2/2019 7/2020 12/2020 Pending