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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Genomics. 2021 Sep 23;113(6):3864–3871. doi: 10.1016/j.ygeno.2021.09.016

Figure 4.

Figure 4.

Validation results for CNN RNA editing models. A. Location of the ADAR1 KO with CRISPR/Cas9. B. Western blot shows the successful knockout of ADAR1. C. ROC curves suggest the excellent performance of CNN Alu and non-Alu models on the independent validation set of novel RNA editing sites. Models used 50-nucleotide flanking sequences for upstream, downstream, and bi-directional modes. D. Confusion tables display both true positive and true negative validation results for both Alu and non-Alu models.