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Inhibition of apoptotic (sub-G1) ELL-expressing 293 Tet Off cells by addition of the zVAD-fmk caspase inhibitor
| Time (h) | Tetracycline | Inhibitor | % of cells
|
|||
|---|---|---|---|---|---|---|
| Sub-G1 | G1 | S | G2/M | |||
| 24 | + | None | 4.9 | 55.4 | 17.3 | 22.4 |
| − | zVAD-fmk | 11.2 | 28.3 | 19.8 | 40.7 | |
| − | zFA-fmk | 21.7 | 22.9 | 19.1 | 36.3 | |
| 48 | + | None | 9.0 | 54.2 | 16.0 | 21.3 |
| − | zVAD-fmk | 17.3 | 34.4 | 18.3 | 30.5 | |
| − | zFA-fmk | 33.1 | 30.5 | 14.5 | 23.7 | |
| 72 | + | None | 4.6 | 54.3 | 18.2 | 22.9 |
| − | zVAD-fmk | 39.9 | 26.5 | 10.7 | 21.9 | |
| − | zFA-fmk | 64.0 | 19.0 | 6.7 | 10.3 | |
