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. 2021 Dec 14;11:23956. doi: 10.1038/s41598-021-03214-x

Table 5.

RORs for depression and anxiety AEs over 65 years old.

Alendronate Zoledronate Risedronate Ibandronate Denosumab
Depression ROR (95% CI) 3.60 (2.82–4.59) 0.97 (0.68–1.39) 1.45 (0.68–3.08) 1.08 (0.68–1.74) 0.63 (0.46–0.85)
Anxiety ROR (95%CI) 2.28 (1.84–2.84) 0.32 (0.21–0.50) 1.43 (0.80–2.56) 0.26 (0.13–0.52) 0.26 (0.18–0.36)

Significant values are in bold for positive and italic for negative correlations respectively.