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. 2021 Dec 14;12:7190. doi: 10.1038/s41467-021-27329-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — a Spearman correlation of drug responses in HL-60 cells in response to 72 h 100 nM AZD3965, 100 nM pictilisib, or 100 nM GSK2194069 treatment quantified as AUC values. Drugs that showed a reduced sensitivity in response to drug treatment are marked in blue, whereas drugs that showed an increased sensitivity are marked in red. b Dose–response curves of the drugs highlighted in a as percentage survival. Black curves are baseline and red curves are in response to the respective drugs. Error bars indicate standard deviation of the mean of technical duplicates.