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. 2021 Dec 10;15:4961–4972. doi: 10.2147/DDDT.S330059

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© 2021 Yang et al.

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The effect of GO-PEI-PEG-CPP/siRNA on breast cancer cell growth in vivo. (A-E) The nude mice were injected with MDA-MB-231 cells and were treated with siRNA, GO-PEI-PEG/siRNA, or GO-PEI-PEG-CPP/siRNA. (A) The body weight was remarketed. (B) The tumor volume was shown. (C) The tumor weight was shown. (D) The tumor size was shown. (E) The level of ki-67 was measured by IHC and apoptosis was analyzed by TUNEL staining (10 x objective). Data are presented as mean ± SD. Statistic significant differences were indicated: *P < 0.05, **P < 0.01, ***P < 0.001.