FIGURE 1.

Overexpression of miR‐107 inhibits proliferation, migration, and invasion and promotes apoptosis of glioma cells. (a) Expression of miR‐107 in normal (n = 10) and glioma tissues (n = 23) examined by RT‐qPCR; (b) Expression of miR‐107 in normal brain glial cells (Heb) and in glioma cell lines (U251, A172, and T98G) examined by RT‐qPCR; (c) Expression of miR‐107 in A172 and T98G cells after miR‐107 mimic transfection examined by RT‐qPCR; (d) Proliferation of A172 and T98G cells determined by the EdU labeling assay; (e) Migration and (f) invasion abilities of A172 and T98G cells examined by the transwell assays; (g) Apoptosis rate of A172 and T98G cells determined by flow cytometry. Data were collected from three independent experiments and presented as mean ± SD. In (a), each spot indicates a sample; differences were compared by unpaired t test (a, c, d, e, f, and g) or one‐way ANOVA (b), *p < .05 versus Normal/Heb/NC mimic