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. 2021 Dec 11;31:110–125. doi: 10.1016/j.jot.2021.11.004

Figure 10.

Figure 10

New bone formation within the femur defects at 12 weeks post-surgery. (a) 2D micro-CT images of implantation area. The circles indicate sagittal plane, rectangles indicate coronal plane. (b) 3D micro-CT images of mineralized bone formation. The circles indicate the original defect areas. (c) 3D micro-CT reconstruction images of implant areas. Orange regions indicate new bone. (d) Quantitative analysis of micro-CT of bone regeneration. Bone volume fractions (BV/TV), trabecular thickness (Tb.Th), trabecular number (Tb.N), trabecular spacing (Tb.Sp), bone mineral density (BMD). Each data point represents the mean ​± ​standard deviation (n ​= ​3), statistically significant differences are indicated as ∗ P ​< ​0.05, ∗∗P ​< ​0.01, ∗∗∗P ​< ​0.001, ∗∗∗∗P ​< ​0.0001.