Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 1;12:794882. doi: 10.3389/fmicb.2021.794882

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Zhang, Li and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Viral evasion of immunity via antagonization of TRIMs. Some TRIMs (green) positively regulate innate immune response. Viral proteins (orange) antagonize these TRIMs to reduce the production of type I IFNs and inflammatory factors. BPLF1, the deconjugases of HSV; E6, the oncoprotein of HPV16; MP, the matrix structural protein of NiV; NS1, the nonstructural protein 1 of IAV; NSs, the nonstructural protein NSs of SFTSV; NP, the nucleocapsid protein of SARS-CoV, MERS-CoV, or SARS-CoV-2; tAg, the small t antigen of JCV; Us11, the Us11 protein of HSV-1; VP35, the VP35 protein of EBOV; 3B, the 3B protein of FMDV; 48, K48-linked polyubiquitination; and 63, K63-linked polyubiquitination.