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Viral evasion of immune response via induction of TRIMs. Some TRIMs (green) negatively regulate innate immune response. Viral proteins (orange) can utilize these TRIMs to reduce the production of type I IFNs and inflammatory factors. USP7, the ubiquitin-specific peptidase 7 of SeV; 48, K48-linked polyubiquitination; and 63, K63-linked polyubiquitination.
